Digital microfluidics

With the rise of theranostics and personalized medicine, medical centers are increasingly in need of a wider variety of specialized radiotracers—tracers that can be produced on-site in small quantities, tailored specifically for individual patients. To meet this growing demand, a digital microfluidic automation system designed for radiopharmaceutical synthesis has been developed, perfectly suited for both research and preclinical stages.

 

Microfluidic environment

  • Reagent and precursor consumption is 90% lower than normal.
  • Faster response efficiency
  • Multiple parallel reaction channels

The digital microfluidic automated radiopharmaceutical synthesis system, installed in a hot cell and paired with radioactive isotope sources, serves as a versatile tool for developing and producing radiotracers in a uniquely innovative microfluidic environment. Thanks to microfluidic technology, the system requires minimal reagents and precursors, enables rapid synthesis, and offers superior control over process parameters.

 

Offer flexible work arrangements

  • Fully Automatic Mode
  • Optional reaction pathway
  • Reusable chips
  • Controllable temperature, up to 150°C

The digital microfluidic automated radiopharmaceutical synthesis system can perform synthesis in manual mode or carry out fully automatic synthesis.

 

 

Synthesize a variety of tracers

  • 18 F-Marker Tracer: Al 18 F-NOTA-octreotide, 18 F-water-phase fluorophosphorus compound
  • 68 Ga-labeled tracer: 68Ga-DOTA-TP-FAPI

The digital microfluidic automated radiopharmaceutical synthesis system, based on a unique microfluidic column structure, effectively prevents cross-contamination. The following radioactive isotopes have already been successfully used in the digital microfluidic automated radiopharmaceutical synthesis system: 18 F and 68 Yeah.

 

 

Patent Name: An Automated Radiopharmaceutical Synthesis System and Method Based on Digital Microfluidics Application Number: CN202510303386.1